In this case II you will modify the simulation to make it more realistic. In the natural environment, not all genotypes have the same rate of survival; that is, the environment might favor some genotypes while selecting against others. An example, is the human condition of sickle cell anemia. This is a disease caused by a mutation on one allele, and individuals who are homozygous recessive often do not survive to reach reproductive maturity. For this simulation you will assume that the homozygous recessive individuals never survive (100% selection against) and that heterozygous and homozygous dominant individuals survive 100% of the time.
Procedure
1. Using the Net Logo Hardy Weinberg model you will run a simulation of a population of randomly heterozygous individuals with an initial gene frequency of .5 for the dominant allele A and the recessive allele a.
2. Set up your “population size” to 500.
3. On the bottom left side of your simulation set your “max- generation” to 100.
4. Select the species you would like to observe... turtles, humans, etc...
5. Move the “selection against yellow” slider to 100%
6. Click on the “set up” button.
7. Click on “go.”
8. Monitor the population closely by observing the species and graphs (genotype, phenotype, and allele)
9. Analyze the data after 100 generations and complete the table below.
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Case I Ideal Hardy Weinberg Population
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Number of Each Frequency
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Sketch the Graph
(create a legend with different colors)
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Initial Data
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Resultant Data
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Genotype Frequencies
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AA =
Aa =
aa =
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AA =
Aa =
aa =
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Total:
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Phenotype Frequencies
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yellow =
blue=
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yellow =
blue=
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Total:
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Allele Frequencies
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A=
a=
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A=
a=
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Total:
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Case II Selection Data Analysis
